| Date | Home | Away | Result |
|---|---|---|---|
| 5/16/25 1:00 PM | FC Famalicao | Casa Pia AC | 2-1 |
| 5/16/25 1:00 PM | Rio Ave FC | FC Gil Vicente | 1-1 |
| 5/17/25 12:00 PM | Sporting Braga | Benfica Lisbon | 1-1 |
| 5/17/25 12:00 PM | Sporting Lisbon | Vitoria Guimaraes | 2-0 |
| 5/17/25 12:00 PM | AVS Futebol SAD | Moreirense FC | 0-3 |
| 5/17/25 12:00 PM | FC Arouca | Boavista Porto | 4-1 |
| 5/17/25 12:00 PM | Estoril Praia | CF Estrela Amadora | 4-0 |
| 5/17/25 12:00 PM | SC Farense | Santa Clara | 1-2 |
| 5/17/25 12:00 PM | FC Porto | Nacional Funchal | 3-0 |